Oral fast dissolving film (FDF) is one such novel approach to increase consumer acceptance by virtue of rapid dissolution, self administration without water or chewing. Oral fast dissolving film is relatively a new dosage form in which thin film is prepared using hydrophilic polymers, which rapidly dissolves on tongue or buccal cavity. The film is placed on the top or the floor of the tongue. It is retained at the site of application and rapidly releases the active agent for local and/or systemic absorption. Different polymers like Pullulan, HPMC E3, HPMC E5, HPMC E6, HPMC E15, HPMC K4M, Carbopol 940, PVP, Chitosan, Gelatin and PVA were used for preparation of FDF. Films with Pullulan and combination of HPMC E series showed transparent appearance, fast disintegration and dissolution. The prepared films were evaluated for their appearance, folding endurance, disintegration time.
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